Ozonated magnesium oxide is the star ingredient in our bestselling MagO7 for good reason. (Note: NBPure MagO7 used to be called Aerobic Life MagO7; for more on the history of MagO7, see From Aerobic Life MagO7 to MagO7: A Bestselling Supplement’s History.
Magnesium oxide (MgO) is a salt that combines both magnesium and oxygen. Its action on the digestive tract is well established. When in the presence of the acid environment of the stomach, it undergoes a conversion process. The result is a compound that increases the osmotic pressure of the fluid inside the digestive tract, which then increases the rate at which stool is excreted.
More specifically, this increased pressure in the intestines promotes the transfer of water to the intestinal tract, increasing the water content and volume of the stool. This fluid-swollen stool then stimulates the intestinal wall to help expel the waste.
This is just one reason why our proprietary formula for MagO7 (with a capital O, not a zero; it’s not Mag07) gets guaranteed relief. Just take before bed for a gentle poop come morning.
Magnesium Oxide: Backed in Research
Numerous recent studies confirm the constipation benefits of magnesium oxide. In one 2019 study, published in the Journal of Neurogastroenterology and Motility, magnesium oxide significantly improved Bristol stool form changes and significantly improved colonic transit time. Since colonic transit time is significantly slowed in those with constipation, improving this is a key indicator of constipation relief. What’s more, researchers found that in using magnesium oxide to relieve constipation, overall quality of life also improved in those who had trouble passing stools.
Another recent study compared magnesium oxide to a plant-based laxative, senna. Researchers found that both were effective in improving the frequency of bowel movements, reducing constipation, and improving quality of life. But senna use has been linked to side effects such as stomach discomfort, nausea, and stomach cramps. Our proprietary MagO7 formula does not have the same side effects.
In one double blind and randomized clinical trial in Japan, published in the journal Nutrients, it was found that magnesium oxide was as effective as a probiotic in managing functional chronic constipation in children. While the probiotic had the additional effect of nourishing the gut microbiome with beneficial bacteria by the nature of how it works, magnesium oxide did not.
This is why NBPure recommends that MagO7 be used in conjunction with a regular course of gut-nourishing and balancing probiotics and fiber like those found in NBPure’s Daily Multi-Fiber and Poobiotics, a probiotic supplement specially formulated for better poops.
The recent research on magnesium oxide has convinced The American College of Gastroenterology (ACG) and the American Gastroenterological Association (AGA) to issue a new clinical practice guideline for treating chronic idiopathic constipation (CIC) in adults. This new guideline recommends magnesium oxide for constipation as one of two evidence-based treatments. This was the first joint clinical practice guideline developed by both organizations. The guideline was published in both societies’ scientific journals.
This is why MagO7 has been reported by users to give reliable relief for the constipation associated with GLP-1 drug protocols.
In addition to its gut benefits, some research has found that magnesium oxide may also help reduce migraine headaches.
Keep in mind that magnesium oxide is not intended to be a magnesium supplement as it’s less bioavailable than other forms of magnesium like magnesium citrate or magnesium glycinate. Instead, it’s a proven, gentle effective treatment for constipation that has been used for hundreds of years.
